“Cystic Fibrosis: A Heterozygote Advantage” – The Title of the Next Hit Movie

By Kelly Bonnville If you’ve ever seen “Five Feet Apart”, a 2019 movie starring Cole Sprouse and Haley Lu Richardson, which tells the dramatic love story of two teenaged cystic fibrosis patients who can never be together due to their disease, you may be under the impression that cystic fibrosis mainly involves not being able … Continue reading “Cystic Fibrosis: A Heterozygote Advantage” – The Title of the Next Hit Movie

Strength in numbers: extra copies of the TP53 gene helps elephants fight cancer

Today’s story begins with Peto’s paradox – the observation that larger animals should have higher cancer incidence than smaller animals, but don’t (1).  Fundamentally, cancer is caused by DNA damage.  Large animals have many cells and usually also have long lifespans.  As a result, their numerous cells duplicate many times and are exposed to a … Continue reading Strength in numbers: extra copies of the TP53 gene helps elephants fight cancer

Man’s best friend– since when?

The dog is the only large carnivore that has been fully domesticated and one the few domesticated animals that was not kept primarily for food. Despite their widespread adoption into human cultures today, relatively little is known about the early events in the history of dog domestication. When and where did dogs originally become domesticated? Russ Corbett-Detig explains.