Strength in numbers: extra copies of the TP53 gene helps elephants fight cancer

Today’s story begins with Peto’s paradox – the observation that larger animals should have higher cancer incidence than smaller animals, but don’t (1).  Fundamentally, cancer is caused by DNA damage.  Large animals have many cells and usually also have long lifespans.  As a result, their numerous cells duplicate many times and are exposed to a … Continue reading Strength in numbers: extra copies of the TP53 gene helps elephants fight cancer

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